Terence J. Colgan, MD, FRCPC, FCAP, MIAC

I am a diagnostic and academic pathologist, a medical doctor who specializes in the diagnosis of disease through the microscopic study of human tissues and fluids. These methods are known as Surgical Pathology and Cytopathology and are essential to the diagnosis and management of many illnesses especially cancer. As a professor my research programme is focused on the prevention and detection of gynaecologic cancers, and teaching today's and tomorrow's practitioners. My GoogleScholar profile tracks where my research is being cited. My current positions include:

• Head of Gynaecological Pathology and Cytopathology at Mount Sinai Hospital and Associate Staff at the University Health Network
• Professor in the Departments of Laboratory Medicine and Pathobiology and Obstetrics and Gynaecology at the University of Toronto
• Past-Chair, Curriculum Committee, College of American Pathologists
• Associate Editor for Cancer (Cytopathology)
• Editorial Board Member for International Journal of Gynaecological Pathology and Journal of Lower Genital Tract Disease
• Associate Editor, Anatomical Pathology, for Archives of Pathology and Laboratory Medicine

I also work with Canadian and international governmental, non-governmental and professional organizations, including:

• American Society for Colposcopy and Cervical Pathology
• College of American Pathologists
• Canadian Association of Pathologists

Placental Molar Disease Diagnostic Service

Along with Mount Sinai Hospital colleagues Drs. Chang and Kolomietz and I have established a Placental Molar Disease (PMD) Lab Diagnostic Service which focuses on the diagnosis of placental hydatidiform molar disease. Hydatidiform molar disease is a major precursor of life-threatening gestational trophoblastic disease. Through the combination of pathologic and molecular analyses the PMD Diagnostic Service has improved the accuracy and precision in the diagnosis of molar disease. The PMD Diagnostic Service is capable of performing histologic, immunohistochemical, microdissection, and genotyping (QF-PCR using Aneufast® kit) procedures on routine archived formalin fixed paraffin embedded pathology specimens of suspected moles. No additional specimen collection is necessary.

These analyses are interpreted by both a gynaecologic pathologist (Drs. Colgan/Chang) and a laboratory geneticist (Dr. Kolomietz) and a final consultation report issued. Most late complete moles can be diagnosed using routine histopathology only. Nevertheless, in some of these cases the Service will be able to detect familial complete mole which should be suspected in cases of repeated molar disease or prior pregnancy loss. In many cases of early mole precise diagnosis and classification may be challenging. Women with such suspected mole would usually use contraception and be monitored using periodic beta-HCG measurement for several months. Morphologic mimics of moles among this group of women can now be identified, and these women may resume pregnancy attempts immediately.

Inquiries regarding the PMD Diagnostic Service should be directed to 416-586-4800 x2296. All other surgical pathology consultation inquiries can be made via my Contact page.